Summoners!
Here’s my guide for Act 4.2.3 “Straight Outta Queens” in Marvel Contest of Champions.

General Thoughts:
Act 4.2.3 introduces the concept of Global Nodes to the Story Quest. Global Nodes operate similarly to regular Link Nodes, except they apply to every fight on the map. If you defeat a Global Node, it is removed just like a Link Node would be. Global Nodes are often located on the final node of a quest, so you might not actually be able to remove them. If you restart the quest, all the Global Nodes will go back up, just as with regular Link Nodes.
In the case of 4.2.3, the Global Nodes are located on the main line of the quest, allowing you to take them all down on your way to the boss for an initial completion. For example, the first Black Bolt fight in this quest has a 100% Attack & Health Boost. By defeating Black Bolt, this bonus is removed from all the subsequent fights. To 100% the quest, you’ll need to take on the side paths, which force you to leave Global Nodes up. Depending on your roster strength, you may be able to take multiple side paths on a single run.
I ran all the side paths in one go, but you can break them up into multiple runs as I have below. Remember the more side paths you take, the more Global Nodes you’ll leave up on the final boss.
I didn’t acquire any meaningful new champions or make any important rank-ups while exploring this quest.
If you have questions about the basic attack moves and combos in Marvel Contest of Champions, please check out my MCOC 101: Combos guide.
Best Champs:
Restrictions: Need 1 Science, 1 Cosmic, 1 Skill, and 1 Mutant to 100% Explore.
Global Nodes: +100% Attack & Health (Black Bolt), +100% Attack & Health (Hulk), Stun (Spider-Man), Fury (Electro), +20% Armor (Ronan)
Boss: Yellowjacket
Boss Notes:
Power Sting 2.0
+500% Attack & Health
Lane 1 – Center – Easy Path
Gate: None
Defenders: Black Bolt, Hulk, Spider-Man, Gamora, Electro, Punisher, Ronan, Captain Marvel Classic
Nodes: None
Team: 6-Star Red Skull, 5-Star Captain America Infinity War, 4-Star Aarkus, 4-Star Black Widow Deadly Origin, 4-Star Man-Thing
Tips: This is the easiest and most direct route for initial completion. You’ll remove the Global Nodes along the way.
Lane 2 – 1st Side Path
Gate: Need 1 Mutant Gate
Defenders: Black Bolt, Drax, Scarlet Witch, Black Panther, Daredevil, Elektra, Spider-Man, Gamora, Electro, Punisher, Ronan, Captain Marvel Classic
Nodes: None
Team: 5-Star Captain America Infinity War, 4-Star Aarkus, 4-Star Emma Frost, 4-Star Black Widow Deadly Origin, 4-Star Man-Thing
Tips: None of the side fights pose any real difficulty.
Lane 3 – 2nd Side Path
Gate: Need 1 Skill Champion
Defenders: Black Bolt, Hulk, Hawkeye, Ms. Marvel Carol Danvers, Hulk, Thor, Iron Man, Gamora, Elektra, Punisher, Ronan, Captain Marvel Classic
Nodes: None
Team: 5-Star Captain America Infinity War, 4-Star Aarkus, 4-Star Emma Frost, 4-Star Black Widow Deadly Origin, 4-Star Man-Thing
Tips: None of the side fights pose any real difficulty.
Lane 4 – 3rd Side Path
Gate: Need 1 Cosmic Champion
Defenders: Black Bolt, Hulk, Spider-Man, Gamora, Iron Patriot, Cyclops New Xavier School, Rhino, Star-Lord, Deadpool, OG Vision, Juggernaut, Drax, Punisher, Ronan, Captain Marvel Classic
Nodes: None
Team: 5-Star Captain America Infinity War, 4-Star Aarkus, 4-Star Emma Frost, 4-Star Black Widow Deadly Origin, 4-Star Man-Thing
Tips: This is the most difficult of the side paths.
Lane 5 – 4th Side Path
Gate: Need 1 Science Champion
Defenders: Black Bolt, Hulk, Spider-Man, Gamora, Electro, Punisher, Black Panther, Elektra, Ms. Marvel Carol Danvers, Thor, Iron Patriot, Rhino, Deadpool, Juggernaut, Captain Marvel Classic
Nodes: None
Team: 5-Star Captain America Infinity War, 4-Star Aarkus, 4-Star Emma Frost, 4-Star Black Widow Deadly Origin, 4-Star Man-Thing
Tips: Just watch your matchups on the hidden nodes as there is a Rhino, Deadpool, and Juggernaut.
My Roster:

Jump To:
Act 4.1.6 – “Trust” – Level 41
Act 4.2.1 – “Linked Might” – Level 42
Act 4.2.2 – “The Guillotine Drops” – Level 43
Act 4.2.3 – “Straight Outta Queens” – Global Nodes
Act 4.2.4 – “Asgard’s Champion” – Level 44
Act 4.2.5 – “Dark Presence” – Level 45
Act 4.2.6 – “Defiance” – Hidden Roadblock
Act 4.3.1 – “Triumphant Return” – Level 46
-Dano357
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